Services

ZiP's in-house recombinant protein production yields large quantities of highly functional and stable recombinant proteins. Current production includes reverse transcriptases, DNA polymerases and custom antigens with capability for customer-requested proteins. These proteins are applicable for a range of molecular diagnostic tests, including those used with ZiP Test Systems, and come at a low-cost and with secure supply chain.

ZiP has a diverse team of research scientists and in-house bioinformaticians developing novel low-cost molecular diagnostic assay chemistry that can run on ZiP Test Systems. Assays will operate in simple fluidic cartridges with a sensitivity comparable to PCR and a rapid time to result of less than 30 minutes. 

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ZiP has optimised lyophilisation processes to increase stability of assay chemistry and to advance assay and cartridge design. Using state-of-the-art technology, ZiP can freeze-dry whole assay solutions as cakes in tubes, or as spherical beads. Lyophilised material undergoes in-house quality control processes such as determination of functional activity, moisture analysis, structural stability and digital image analysis.

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ZiP provides services for manufacture of lateral flow strips (line-based or array-based), full assembly of cartridges, and supply of customised reader instruments. ZiP has a proprietary array production printing capability suitable for printing of nanolitre protein spots or particles on lateral flow membranes or functionalised plastic surfaces. Typical array formats suits strips from 25 spots (in a 5 by 5 compact array format) up to 100 spots.

ZiP has a wide range of in vitro cultured PC2 organisms, developed for current in-house diagnostic test optimisation and evaluation. Contact us for species and strain availability.

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ZiP has a dedicated point-of-care study centre available for clinical validation and usability studies. This centre enables simulation of community-based diagnostic testing indicative of general practice clinics, community screening and hospital emergency departments.

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