Clinical trials are completed to ensure ZiP Diagnostics test platforms are specific and sensitive in the detection of target virus/bacteria in the intended population. The following trials are underway.
Field validation of the ZiP-CoVx-P2 diagnostic system for detection of SARS-CoV-2 virus
Field validation of the ZiP-CoVx-P2 diagnostic system will commence in Ghana, November 2021. This study is supported by the British Society of Antimicrobial Chemotherapy (BSAC) grant. Field trips are being undertaken to collect swab samples (throat, nasal, and saliva) in communities where high- and low-income earners reside, as well as in public areas such as markets, schools, and malls. Individuals recruited will be those who display (symptomatic) or do not display (asymptomatic screening) COVID-19 symptoms. Samples will be stored in biobanks until these diagnostic systems arrive in Ghana.
Lead investigator: Dr. Charles Narh
Co-investigators: Assoc/Prof Jack Richards, Dr. Lydia Mosi and Mr. William Hopper
Institutions: ZiP Diagnostics Pty Ltd, Collingwood, Australia. Noguchi Memorial Institute for Medical Research (NMIMR), University of Ghana. Biochemistry, Cell and Molecular Biology (BCMB), University of Ghana, Legon, Ghana. West African Centre for Cell Biology of Infectious Pathogens (WACBIP), University of Ghana, Ghana.
Obtain fresh samples from volunteers to help ZiP evaluate and optimise new point-of-care diagnostic tests for infectious diseases
The test evaluation, development and implementation (TEDI) study obtains fresh specimens from up to 50 volunteers. Recruitment and sampling will be completed at Victorian Infectious Diseases Service, Royal Melbourne Hospital (RMH). Samples will be transferred to ZiP Diagnostics Pty Ltd and used as negative clinical matrixes to optimise novel diagnostic tests and for early-stage analytical validation of these tests.
Lead investigator: Assoc/Prof Joe Sasadeusz
Co-investigator: Assoc/Prof Jack Richards
Study Coodinators: Dr. Jennifer Audsley (RMH), Dr. Jacqueline Flynn (ZiP)
RMH Research Nurse: Ms. Jo Patterson
Institutions: ZiP Diagnostics Pty Ltd, Collingwood, Australia. Royal Melbourne Hospital, Victorian Infectious Diseases Service Outpatient Department, Parkville, Australia.